I will never forget when the sequencing and technique was poop pooed 💩, by an individual of stature importance and knowledge. Thanks Dr. Rose , you stood your ground …. Thank u for your knowledge and wisdom.
Thanks Dr Jessica Rose 🌹 it does explain a lot many I will view it many times over so I can understand it to explain to others around me but it also explains a lot about the health issues of the cOVID-19 injectables affecting the heart as you know electrical impulses are very critical to the function arrhythmia and a fib , the basic functionality of the heart ,
if that affects on a nano level it totally makes sense why there is such an increase (epidemic ) issues of heart elements in the world……
Not related. Gel electrophoresis is a tool that pulls laboratory specimens apart. The knowledge of which base pair attaches where, in DNA, would exist even if no electricity had been used to study the subject.
Many years ago when I was interning at a cancer institute, we had an electrophoresis machine in our lab that got occasional use. Back then, NASA had persuaded some NIH scientists that electrophoresis would work faster and with better purity, if the tests were run aboard the Space Shuttle while in orbit. Gravity squeezes the gel and some of the pores get bigger than others, causing incomplete separation and flawed data. The newer methods Dr Rose describes, do not use electrophoresis any more, so nobody ended up using the Space Shuttle for genetics research.
What's happening in vaxx-induced heart disease needs further study so lives can be saved, but appears to result from a poison that's formed when the vaxx reacts with our immune system. The poisoned heart muscle becomes weak.
Possibly an electrical problem is de-myelination. Myelin is an electrical insulator our bodies make from cholesterol, that prevents signals traveling on nerve bundles, from jumping to the wrong nerve and blocking communication. That's one of many possible results of a toxin attack on the heart, and we really need to study them all until we arrive at an explanation of what happened.
Those of us who suspect the C19 virus was designed as a weapon have much to chew on. Getting at the truth will probably require granting immunity from prosecution to any war criminals who come forward with the whole truth
Hi Bob. I’m vaccine injured. Me and many others injured felt electrical or electricity going through whatever bodily injury you got. in my case, vision and loud tinnitus I felt electricity going through my brain for a time one evening. It was scary. I’d love to know what caused that. Also, many people got MS after the shot or MS type symptoms. That paper is no longer found on google but someone found it on the way back machine. At first I thought it was just me feeling the electrical feeling but discovered on real not rare so many others experienced it.
I was referring to the process of how the heart works at the nanotechnology vaccine injectable interferes with that process it would explain the heart issues not the mechanism of sequencing I wasn’t referring to that
In my 'Forrest Gump' of a career-life, I was at TIGR when Craig Venter and Claire Fraser sequenced the genome of microbes, then finally collaborated with NIH Human Genome Project to get a full human sequence. I was on their human subjects/ Animal care oversight board. [We were from Buffalo SUNY and worked with Darrell Doyle PhD making monoclonals in the early nineties. ]
"See what competition can do? Imagine a world where there’s only the NIH in control of everything. We need independent companies, and we need competition. "
I said something similar, like , 'everyone is competing, just like a basketball game,' to the press who interviewed me at that time. [Collins clearly did not like to be forced to actually produce scientific work. Too busy playing his banjo and quoting Bible verses... had to maintain that 'innocent image']
TIGR collaborated with everyone, and my hardest job was trying to convince Craig to NOT give away all his DNA to be used in experiments. Privacy issues!! Especially for related family. But he was a man on a mission, with big visions.
Excellent and timely review. Thank you. As a primary care doctor being inundated with various commercial products and innovations, combined with the “individualized” optimal health concept, I would ask if you can suggest a contemporary “primer” text or source for clinical application ?
1. Oxford Nanopore sequencing- is freaking cool AS. Totally makes sense why you shall utilise nothing else in genomee-land😉😂😂
2. The DARPA brainstab tools- uh yeps. The level of nudge involved on the public, for a testing mechanism that so many knew, was nowhere near reliable enough to be used diagnostically, was very interesting. Combined with the changes at regulatory agencies like TGA/FDA, to the registering parameters- it was like the freaking wild west! But I deviate slightly on your theory. Reality is 23&Me and the multitude of other DNA private companies, have had a lot of DNA information floating in the ether, for quite a while now, which has all been sold multiple times over. So I doubt it was a DNA dump exercise. If anything, I think it was more a refinement tool, training tool and possibly a hunting tool. For what? Who really knows, but it certainly wasn't for SARSCov2!😉🤨
3. The bit in this article that makes me C&C factory-
"...the long DNA is cut into shorter segments of specific lengths using sound waves....".
Now THATS very interesting. Things that make me go Hmmm?! BTJMO 😉🤔😉
The problem is the "switching on and off" certain genes without knowing the reaction of other genes. It's one giant experiment with humans as the test subject.
And that's the arrogance of their assumption of the "switching on and off" that I personally object to. They don't even know WHERE all the switches are, WHAT they switch on/off, but also haven't accounted for the unlimited unknown switches floating in the "junk DNA", that are activated by environmental, as well as psychoneuroendocrinoimmunological influences. 🤦♀️🤦♀️🤦♀️🤐🙄
Oh I couldn't agree more! I once had a conversation with a tip UK geneticist who swore by gene therapy. I told him his methods were like playing football without knowing the rules. He never rebutted that statement.
Epigenetics is generally the study of how environment and time affects the genetic makeup of a lifeform. Until recently, epigenetics was left to nature that sorted out which animals needed wings to survive and which animals needed flippers albeit very slowly over many years.
Thanks for some serious mind-fodder as a subset to the science DNA sequences. I need to ‘chew’ to role of government, property rights, and human rights aspects a bit but when you raise the moral question with respect to advancement in scientific knowledge you truly are asking about the future of civilization. I may try to elaborate my thoughts in a later comment.
So very cool Jessica! The capacity of the human brain made up of base pairs to figure out how to sequence base pairs .......Some kind of wonderland there !
Never had a swab up my nose… but how do I know they didn’t sell my blood sample used for a routine lab series? I don’t of course I always hand write in things on consent forms like: I do not give permission for any of my bodily fluids or sample to be sold and/or used for genomic analysis or sequencing. Not that anyone has ever paid attention to this… but I state it anyway. I probably have some bad mark on my identification somewhere for being a dissident, and therefore limit my interactions with the medical industrial complex…. Where let’s face us we are considered Guinea pigs who have been duped for paying for the privilege of being experimental subjects. No jabs either.
it depends what you have and what you want to do - single genes, 1-100 amplicon targets, etc - use Sanger, for example. NGS is great if you have a lot of genes, or a low starting amount of sample, for example.
Seems like if there is a gene responsible for any of a number of maladies, they should be able to find it really fast. This should blow up the gene hypothesis for 99.99% cases of autism really really fast.
But you end on a really terrifying note. Sequencing a person’s entire genome without their explicit consent seems like it should be illegal in a functioning society.
The Olympics in China in 2022 and their mandatory athlete swabbing definitely gave me the creeps!
Thank you for another enlightening and entertaining article that reinforced my decision to keep being a paid subscribers. AS an aside I am dubious about the future of gene swapping to correct disease as I am dubious about how great AI will be. If correcting genes was effective long term, why haven't these techniques eliminated sickle cell disease. I thought this would happen but I don't see any of the case reports one hears about turning into long term wide spread therapy. It makes me wonder if the body doesn't squash the cells producing the correct hemoglobin. (Yes, I should do a PubMed search and possibly will later.)
Thank you Jessica for your excellent article on DNA sequencing. It brought many memories of pouring and running our own sequencing gels, developing the films and reading and proof reading the sequences without too many mistakes. That's how we identified the 1st mutation in Tay-Sach's disease at Sick Kids Hospital in Toronto in 1988. And to aid reading of the sequences I made a sequence reader called DNA Parrot that consisted of a cursor with 4 buttons and audio and visual feedback and software to enter the sequence into a computer. This device was also able to proofread the sequence. This was 35 years ago, hard to believe. I was marketing it around the world for a few years and sold quite a few of those units.
I will never forget when the sequencing and technique was poop pooed 💩, by an individual of stature importance and knowledge. Thanks Dr. Rose , you stood your ground …. Thank u for your knowledge and wisdom.
Stop sticking your shitty adverts in loads of stacks. Lisa, Beth or whoever you are
See these spams so much. No Thanks.
troll
STOP.
troll.
STOP.
If you want to say something say it. Don't send folks to a scam website.
Thanks Dr Jessica Rose 🌹 it does explain a lot many I will view it many times over so I can understand it to explain to others around me but it also explains a lot about the health issues of the cOVID-19 injectables affecting the heart as you know electrical impulses are very critical to the function arrhythmia and a fib , the basic functionality of the heart ,
if that affects on a nano level it totally makes sense why there is such an increase (epidemic ) issues of heart elements in the world……
Not related. Gel electrophoresis is a tool that pulls laboratory specimens apart. The knowledge of which base pair attaches where, in DNA, would exist even if no electricity had been used to study the subject.
Many years ago when I was interning at a cancer institute, we had an electrophoresis machine in our lab that got occasional use. Back then, NASA had persuaded some NIH scientists that electrophoresis would work faster and with better purity, if the tests were run aboard the Space Shuttle while in orbit. Gravity squeezes the gel and some of the pores get bigger than others, causing incomplete separation and flawed data. The newer methods Dr Rose describes, do not use electrophoresis any more, so nobody ended up using the Space Shuttle for genetics research.
What's happening in vaxx-induced heart disease needs further study so lives can be saved, but appears to result from a poison that's formed when the vaxx reacts with our immune system. The poisoned heart muscle becomes weak.
Possibly an electrical problem is de-myelination. Myelin is an electrical insulator our bodies make from cholesterol, that prevents signals traveling on nerve bundles, from jumping to the wrong nerve and blocking communication. That's one of many possible results of a toxin attack on the heart, and we really need to study them all until we arrive at an explanation of what happened.
Those of us who suspect the C19 virus was designed as a weapon have much to chew on. Getting at the truth will probably require granting immunity from prosecution to any war criminals who come forward with the whole truth
Hi Bob. I’m vaccine injured. Me and many others injured felt electrical or electricity going through whatever bodily injury you got. in my case, vision and loud tinnitus I felt electricity going through my brain for a time one evening. It was scary. I’d love to know what caused that. Also, many people got MS after the shot or MS type symptoms. That paper is no longer found on google but someone found it on the way back machine. At first I thought it was just me feeling the electrical feeling but discovered on real not rare so many others experienced it.
I was referring to the process of how the heart works at the nanotechnology vaccine injectable interferes with that process it would explain the heart issues not the mechanism of sequencing I wasn’t referring to that
A technique used to sequence DNA has nothing to do with vaccination or the way the heart works...
Thanks Jessica, great accessible read.
In my 'Forrest Gump' of a career-life, I was at TIGR when Craig Venter and Claire Fraser sequenced the genome of microbes, then finally collaborated with NIH Human Genome Project to get a full human sequence. I was on their human subjects/ Animal care oversight board. [We were from Buffalo SUNY and worked with Darrell Doyle PhD making monoclonals in the early nineties. ]
"See what competition can do? Imagine a world where there’s only the NIH in control of everything. We need independent companies, and we need competition. "
I said something similar, like , 'everyone is competing, just like a basketball game,' to the press who interviewed me at that time. [Collins clearly did not like to be forced to actually produce scientific work. Too busy playing his banjo and quoting Bible verses... had to maintain that 'innocent image']
TIGR collaborated with everyone, and my hardest job was trying to convince Craig to NOT give away all his DNA to be used in experiments. Privacy issues!! Especially for related family. But he was a man on a mission, with big visions.
- Laura Kragie MD biomedworks.substack.com
wow! awesome comment!
Excellent and timely review. Thank you. As a primary care doctor being inundated with various commercial products and innovations, combined with the “individualized” optimal health concept, I would ask if you can suggest a contemporary “primer” text or source for clinical application ?
The best weapon against totalitarianism is billions of voices saying, "Not only No, but Hell No!"
👍👍 I took 3 things from that excellent piece:
1. Oxford Nanopore sequencing- is freaking cool AS. Totally makes sense why you shall utilise nothing else in genomee-land😉😂😂
2. The DARPA brainstab tools- uh yeps. The level of nudge involved on the public, for a testing mechanism that so many knew, was nowhere near reliable enough to be used diagnostically, was very interesting. Combined with the changes at regulatory agencies like TGA/FDA, to the registering parameters- it was like the freaking wild west! But I deviate slightly on your theory. Reality is 23&Me and the multitude of other DNA private companies, have had a lot of DNA information floating in the ether, for quite a while now, which has all been sold multiple times over. So I doubt it was a DNA dump exercise. If anything, I think it was more a refinement tool, training tool and possibly a hunting tool. For what? Who really knows, but it certainly wasn't for SARSCov2!😉🤨
3. The bit in this article that makes me C&C factory-
"...the long DNA is cut into shorter segments of specific lengths using sound waves....".
Now THATS very interesting. Things that make me go Hmmm?! BTJMO 😉🤔😉
i know right?! everything is vibrating
The problem is the "switching on and off" certain genes without knowing the reaction of other genes. It's one giant experiment with humans as the test subject.
And that's the arrogance of their assumption of the "switching on and off" that I personally object to. They don't even know WHERE all the switches are, WHAT they switch on/off, but also haven't accounted for the unlimited unknown switches floating in the "junk DNA", that are activated by environmental, as well as psychoneuroendocrinoimmunological influences. 🤦♀️🤦♀️🤦♀️🤐🙄
Oh I couldn't agree more! I once had a conversation with a tip UK geneticist who swore by gene therapy. I told him his methods were like playing football without knowing the rules. He never rebutted that statement.
The downstream affect.
The switching issue is the field of epigenetics. Someone commented on epigenetics in this discussion
Epigenetics is generally the study of how environment and time affects the genetic makeup of a lifeform. Until recently, epigenetics was left to nature that sorted out which animals needed wings to survive and which animals needed flippers albeit very slowly over many years.
Right- but now many (functional medicine for instance) are trying to change genetic expression or suppression by hacking "above the gene".
Thanks for some serious mind-fodder as a subset to the science DNA sequences. I need to ‘chew’ to role of government, property rights, and human rights aspects a bit but when you raise the moral question with respect to advancement in scientific knowledge you truly are asking about the future of civilization. I may try to elaborate my thoughts in a later comment.
I will never swap my bad genes for the good ones……I hate to be a saint!
Swab up nose, tongue in cheek?
So very cool Jessica! The capacity of the human brain made up of base pairs to figure out how to sequence base pairs .......Some kind of wonderland there !
Never had a swab up my nose… but how do I know they didn’t sell my blood sample used for a routine lab series? I don’t of course I always hand write in things on consent forms like: I do not give permission for any of my bodily fluids or sample to be sold and/or used for genomic analysis or sequencing. Not that anyone has ever paid attention to this… but I state it anyway. I probably have some bad mark on my identification somewhere for being a dissident, and therefore limit my interactions with the medical industrial complex…. Where let’s face us we are considered Guinea pigs who have been duped for paying for the privilege of being experimental subjects. No jabs either.
Thanks! Is the accuracy of the other two the same or better than Sanger?
it depends what you have and what you want to do - single genes, 1-100 amplicon targets, etc - use Sanger, for example. NGS is great if you have a lot of genes, or a low starting amount of sample, for example.
this video gives a nice explanation: https://www.youtube.com/watch?v=Wpww8bb63zU
they're both accurate
Seems like if there is a gene responsible for any of a number of maladies, they should be able to find it really fast. This should blow up the gene hypothesis for 99.99% cases of autism really really fast.
But you end on a really terrifying note. Sequencing a person’s entire genome without their explicit consent seems like it should be illegal in a functioning society.
The Olympics in China in 2022 and their mandatory athlete swabbing definitely gave me the creeps!
Noli me tangere. That is all, folks.
Thank you for another enlightening and entertaining article that reinforced my decision to keep being a paid subscribers. AS an aside I am dubious about the future of gene swapping to correct disease as I am dubious about how great AI will be. If correcting genes was effective long term, why haven't these techniques eliminated sickle cell disease. I thought this would happen but I don't see any of the case reports one hears about turning into long term wide spread therapy. It makes me wonder if the body doesn't squash the cells producing the correct hemoglobin. (Yes, I should do a PubMed search and possibly will later.)
Thank you Jessica for your excellent article on DNA sequencing. It brought many memories of pouring and running our own sequencing gels, developing the films and reading and proof reading the sequences without too many mistakes. That's how we identified the 1st mutation in Tay-Sach's disease at Sick Kids Hospital in Toronto in 1988. And to aid reading of the sequences I made a sequence reader called DNA Parrot that consisted of a cursor with 4 buttons and audio and visual feedback and software to enter the sequence into a computer. This device was also able to proofread the sequence. This was 35 years ago, hard to believe. I was marketing it around the world for a few years and sold quite a few of those units.