is likely that certain cancer-derived p53 mutants transactivate growth-promoting and oncogenic genes, thereby leading to the progression of the aggressive cancer's?
is likely that certain cancer-derived p53 mutants transactivate growth-promoting and oncogenic genes, thereby leading to the progression of the aggressive cancer's?
is likely that certain cancer-derived p53 mutants transactivate growth-promoting and oncogenic genes, thereby leading to the progression of the aggressive cancer's?
That's mathematically impossible.
And physically impossible. Bc any transfected cell that carries MHC, isn't immuno-privileged will be apoptosized...
So they all already had p53 inhibition,else they'd have apoptosized.