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Jessica Rose's avatar

I really appreciate and love you all, and that includes the guys who run Substack. We really need you!

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Dr Mike Yeadon's avatar

Thank you, Jess. I hope I didn’t alarm you more than necessary with my ever more strident claims that these injections were designed intentionally to injure, kill and reduce fertility in survivors. But that is what my steady gaze is telling me and no one has rebutted what I’ve said. I was in the engine room of many teams involved daily in so-called structure-based (or “rational”) drug design for decades. I also have a training in mechanistic toxicology.

I know how extraordinarily sensitive we all were to the “maybe this aspect might represent a toxicological issue” at all times. Two main failure modes of new mechanisms of action pharmaceuticals are (1) failure to show efficacy (our medical hypothesis was wrong) & (2) safety issues in the context of the intended use precluded further development.

Failures like these are ones daily reality. We’re nowhere near as clever at guessing ahead of time what’s going to work and what’s going to be safe.

A general rule of thumb is that powerful mechanisms tend not to be very safe. That’s probably why most drugs are either tepid in their usefulness or carry liabilities that have to be tiptoed around.

This dictum wasn’t popular but I wasn’t in the business of trying to be popular.

In the case of public health interventions, the priority is SAFETY, not efficacy, because huge numbers of people are going to be get exposed who never were at risk.

Knowing what I do, there was not the slightest possibility that the intentions here were other than to cause harms.

You’re right: they’re going to do it again.

Every version of mRNA-based products is going to be unavoidably, axiomatically unsafe and this is well known to my peers involved in their design.

Even at this late stage, I issue this demand that they stop what they are doing, resign and join me in the trenches.

It wouldn’t take many of you to push these lunatics into the sea where they belong. But I need back up.

Thank you, Jess. Your clear thinking is more than good enough.

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