In light of DNA discovered in commercial vials as per the precautionary principle...
Opinion/recommendation: the modified mRNA-LNP platform needs to have a moratorium slapped on it, and all existing vials should be confiscated and protected for testing
Hi everyone, there are currently a number of articles being written about the residual DNA found in Pfizer and Moderna COVID-19 product vials. This is good. The presence of many, many tiny (potentially undetectable unless you use the right assay) DNA fragments in the commercial vials is indeed an extremely important issue, and one that warrants mass acknowledgement and subsequent follow-up and continued investigations.
Ultimately, we need to find out (like yesterday) if any of this DNA got integrated into any human genomes. In addition to testing a lot more vials, filling in the data gaps for the dose response curve to prove causal effects of DNA:SAEs (if they exist), we need to test injected people’s stem cells and germ line cells for integration of any of this DNA. Once we can prove in a large enough sample of injected individuals that integration did not occur, we can finally breathe a sigh of relief and definitively state that integration of this foreign contaminant DNA is not an issue.
This affects all of us, especially if shedding of LNPs is an issue. That’s for another article.
Here’s our preprint on this subject matter. Since we uploaded it to the OSF preprint server on October 19, 2023, it has garnered 59,659 views and 4,055 downloads so far. People are interested. And they should be. If you want a breakdown of some of the methodologies or sequences, please go to Kevin’s incredible Substack.
Something I want to make very clear here - because I can see this most important message getting lost in the cross-fire - is the following:
The problems associated with the modified mRNA COVID-19 injectable products is not only a problem of DNA contamination. This is yet an additional problem associated with the modified mRNA products. We do not want to run the risk of giving the manufacturers a pass if they simply ‘promise’ to clean out the residual DNA at the end-stage purification step for modified mRNA synthesis. This is NOT going to solve the problems associated with the LNPs, or the use of coding material for a foreign antigen for production by host cells that are very clearly associated with multitudes of serious adverse events.
The platform, and this DNA issue alike, are problematic, and for different reasons.
We must not forget that the LNPs themselves are toxic, and no studies have been done to investigate the effects of the presence of empty LNPs, such as the potential induction of coagulation of red blood cells by zeta potential disruption.
Recommendation: The modified mRNA-LNP platform needs to have a moratorium slapped on it, and all existing vials should be confiscated and protected for DNA testing. It should become illegal to destroy the vials because at this point, it would be destruction of evidence. I am not a lawyer, but that seems clear.
It is in the best interest of the people - the same people whose lives the CDC, HHS, doctors, administrators, and all government entities were trying to protect and save with a safe and effective vaccine - to demand answers now, and to request from their state/provincial representatives the aforementioned recommendations.