I have had RA for 15 years. Early on there was suggestion that the covid vaxx caused inflammation. I did not think it wise to inject an experimental biological with no safety data for RA pts and take anything that might cause inflammation. I requested a covid vaxx medical exemption from GP. My request was denied. I rec’d a long letter from the rheumatology dept I attend in Exeter. The letter explained how important it was that anyone taking drugs such as methotrexate and leflunomide should be vaxxed. The letter was signed by all of the consultants in the dept. I am fascinated to know how these highly qualified doctors reached their decision, since (1) RA pts were not included in covid vaxx trials and (2) not one of those doctors knows what the vaxx contains. Fascinating. Well in Sept, when I go for my annual review, which is now over two years delayed, I will ask the consultant to explain the letter he/she signed.😂😂🤡🌎 should be an interesting conversation.
They never read Dr. Jessica' s Substack, and forgot there are Immunology texts available to review mechanisms of action of the immune system.They failed due diligence to protect their patients.
Well there’s some “science” for you. The real deal. Thank you!
My journey with vaccines in general started after my daughter was born. Home birth, NYC. 1988. 5th floor East Village walk up.
My mother-in-law asked me at one point if I was going to vaccinate my daughter. I was like oh! Let me check into that. My two reference books were “How to Raise a Healthy Child in Spite of your Doctor” and one I can’t quite remember the name written by a doctor that was a resource for new moms, including home made formula. Yes, I was a “hippy” Mom. Anyways, they both had chapters dedicated to vaccines. After reading those I went into shock and fear about vaccinating my daughter. The charts that showed the waning of the diseases prior to the introduction of the vaccines. The increase in polio in Sweden After the vaccines were introduced, etc. I chose to not vaccinate my daughter. Joined a group of new Mon’s who were against vaccinating their babies. Lots of resources and support from a small group of doctors were available back then.
The book “DPT, a shot in the dark” came out.
I was lucky to be able to have a vaccine exemption for my daughter and later my son in NY. That’s gone now.
I never took my kids to the doctor unless absolutely necessary. I had a “first aid” kit that had homeopathic medicines and eichanacea. That was all we every needed. Eichanacea tincture drops immediately upon cold symptoms. Zap! Over. Immune system power booster…
I moved to Woodstock NY in 1990. My new neighbor had two girls close to my daughter’s age. She had chosen to not vaccinate her first child. But she was a Mom who took her child in for all those well baby “checkups” that we were told to do. One time, when her daughter was 18 months old, a healthy thriving energetic child, she was bullied and pressured to give her daughter a vaccine. She caved. Immediately afterwards her daughter had a high fever, became sluggish and despondent and never recovered. She was then diagnosed with leukemia. This was when the periwinkle plant had been discovered as an effective chemotherapy treatment for childhood leukemia, which previously was a slow death sentence. $100,000 later, her daughter fully recovered. Was never given another vaccine and next child not vaccinated. A “coincidence”? She and I don’t think so.
I watched the advent of autism unfold. Read Mothering Magazine. The heartbreaking stories and the doctors who were trying to treat. The articles about vaccine dangers.
When my son was born in hospital in 1996 (I had gestational diabetes) I signed paperwork refusing the Hepatitis B vaccine for my newborn. Who the hell thinks that vaccine is needed at birth?? Or at any point for a child?
Fast forward to Covid. My brother was in full remission from HPV throat cancer for over a year. Got the Covid vaccine. 2 months later his cancer returned aggressively and despite all the treatments, they could not stop it. He died this August. Heart attack is what my sister in law thinks. She found him dead at the side of his bed.
These Covid “vaccines” are Killers. They are in the gene therapy classification which under “normal” circumstances would have to go through 8-10 years of trials. Not 2 months. These are a science experiment that has gone south. Actually to hell. We are inheriting the whirlwind here. With so many lives having been needlessly lost and others’ health irreparably damaged. Beyond a living nightmare.
I feel the same about many other childhood vaccines. That are bombarding an undeveloped immune system with substances that we are not even allowed to know what the ingredients are. “Trust us” “They are safe”. I watched Del and Gert lock horns about vaccines. I am not buying the “herd immunity” stance that Gert is taking. Question, haven’t all the “at risk” population that Gert was referring to already been vaccinated?
Realize this is a rambling post. So few people to talk to about this.
Jessica, you are doing incredible work. Thank you from the bottom of my heart! You are a fearless warrior. A true leader of the tribe of Truth. Be well. Keep riding that wave!
Yes… Thank God she recovered. When I took my son to the doctor because he had a watermelon seed in his ear (!), he and the nurse looked at me like I was a child abuser when I told them my son wasn’t vaccinated. Their hands were practically twitching (literally!) to give him some vaccines. I swear if they could have reported me they would have. On the spot.
Doctors are so poorly educated about vaccines.
I went to Dr. Paul Marik’s trial in Virginia this past fall. To protest and show support. I sat directly behind him in the court room, brought him water. The trial was a nightmare. Lawyer and hospital representative were Horrid.
Afterwards we spoke. He had just read the new Dr. Fauci book. Twice. He stated that he had done a total 180 about vaccines after reading it. Mentioned the word Evil twice.
Big Pharma’s get out of jail free card in 1986 has caused nothing but damage to our children.
As most parents operate from blind obedience to the all mighty doctors. With Big P leading the way.
Thanks be for the light that shines through this covid darkness.... the silver lining maybe, that more and more parents will realize that they've been bought and sold all along...
Thank you for sharing. Can you enlarge upon your disagreement with Dr. Vanden Bossche. The vaccinated are in fact the at risk population, as vaccine induced immunity is much inferior to herd immunity conferred by means of innately-naturally produced immunity according to Dr. Vanden Bossche.
From a colleague: "No discussion on autoimmunity and tolerance is complete without reference to cancer.
Defending against cancer requires controlled autoimmunity and breaking tolerance. Low-affinity self-reactive (LASR) T cells recognize antigens that differ from self by one or more amino acid residues. They are ideally suited to recognize cancer cells and when activated, kill cancer cells.
Animal/plant proteins (xenogeneic antigens), human proteins (allogeneic antigens) that contaminated vaccines/biologics are ideally suited to break tolerance and cause autoimmunity.
In fact, oncologists do exactly that.
Xenogeneic therapeutic cancer vaccines as breakers of immune tolerance for clinical application: to use or not to use?
For experts: Cancer immunology, bioinformatics and chemokine evidence link vaccines contaminated with animal proteins to autoimmune disease: a detailed look at Crohn's disease and Vitiligo
In healthy people, spike levels upon infection should be low and unlikely to cause problems. In the vaccine-damaged (traditional non-covid vaccines), the immune misfiring upon infection can result in high spike protein levels that could cause autoimmunity as you propose.
Jessica, you are a great writer but this is one of your most lucid pieces ever. Will be passing out to medical students to see if they can think at all...Lots thought provoking in here. Many thanks.
Of course, why would you think to include a 3'UTR that has HUMAN RNA in it (part of the AES tumour suppressor and 12s mitochondrial RNA), downstream of two dysfunctional stop codons (because you used Pseudo-uridine which makes them invisible) and not expect any autoimmune disease? Add in the dysregulation of Th17 and IL-6 and make sure your product makes its way to the spleen and there you go. Oh and don't forget a bit of amyloid. A ticking time bomb of autoimmune disease. Well done Ugur, now you can go and do one of your celebratory rituals. What have you got next in line for us? https://pubmed.ncbi.nlm.nih.gov/30638957/
Nice job. Pomegranate peel/extract could help with promoting Treg cells and downregulating the inflammatory cytokines. Too much is not better and can be inflammatory.
"PoPEx differently modulated the expression of activation markers (CD69, CD25, ICOS) and PD1 (inhibitory marker), depending on the dose and T-cell subsets. PoPEx (starting from 12.5 µg/mL) suppressed the production of Th1 (IFN-γ), Th17 (IL-17A, IL-17F, and IL-22), Th9 (IL-9), and proinflammatory cytokines (TNF-α and IL-6) in culture supernatants. Lower concentrations upregulated Th2 (IL-5 and IL-13) and Treg (IL-10) responses as well as CD4+CD25hiFoxp3+ cell frequency. Higher concentrations of PoPEx increased the frequency of IL-10- and TGF-β-producing T-cells (much higher in the CD4+ subset)." (Colic, et al., 2022)
Adequate vitamin D levels are essential for Tolerance and requires adequate magnesium to be possible. Avoiding glyphosate may also be a need for good vit D metabolism.
Another exceptional write up. Well done Jessica! If you're right about over-expression of IL-6, I wonder if there could be a similar mechanism of action in any of the current, non-MRNA vaccines. IL-6 has been shown to up-regulate itself in a positive feedback loop (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077634) leading to MS. I've had my suspicions since I developed gluten intolerance (also autoimmune) not long after my only influenza shot. This is of course, difficult to prove, but a cursory look through OWID shows an inbalance in prevalence of most autoimmune diseases and not surprisingly, they are far less common in S. America, Africa, and Asia. Sensibly, we do not find autoimmune diseases in wild/non-domesticated animals so it wouldn't at all surprise me they are, to a large degree, self-inflicted.
Another hypothesis involves biomimicry and pathogenic priming--that is, the SARS-CoV-2 virus was designed with many human-like epitopes that trigger autoimmunity, especially in immune systems that have had prior exposures to similar coronaviruses (more likely in the elderly).
From the author: "In the case of SARS-CoV-2, B-cell mediated autoimmunity was predicted by 27 autoreactogenic epitopes--1/3 were predicted to target immune cells."
The paper, Unbalanced neonatal CD4+ T-cell immunity. August 27, 2017
does not specifically answer the question posed about the injection of Covid19 products, however the authors advise caution in developing vaccines for infants writing:
caution should be taken as induction of strong Th17-type responses could possibly break the induction of immune tolerance to self antigens and favor the development of autoimmunity. The default generation of Tregs in neonates could furthermore promote the Th17 pathway by producing one of its differentiation cytokine, TGFβ (31–33), which could lead to an uncontrolled inflammatory response
Jessica wrote: Is the spike protein destroying tolerance itself?
Good question. It hit me when I read it that perhaps it is culture wide. Something in the air, water or food has caused lots of people to lose tolerance for themselves and each other. Is it the global application of COVID-19 injectable products?
On another subject. In "You can quote me." You mention your age. My wife and I have talked about that before. We couldn't tell how old you are. Look 37 to us.
A while back you wrote about how you self-treated what was diagnosed as “illness-induced asthma”. Can you tell us more about how you achieved that? Thank you!
I have had RA for 15 years. Early on there was suggestion that the covid vaxx caused inflammation. I did not think it wise to inject an experimental biological with no safety data for RA pts and take anything that might cause inflammation. I requested a covid vaxx medical exemption from GP. My request was denied. I rec’d a long letter from the rheumatology dept I attend in Exeter. The letter explained how important it was that anyone taking drugs such as methotrexate and leflunomide should be vaxxed. The letter was signed by all of the consultants in the dept. I am fascinated to know how these highly qualified doctors reached their decision, since (1) RA pts were not included in covid vaxx trials and (2) not one of those doctors knows what the vaxx contains. Fascinating. Well in Sept, when I go for my annual review, which is now over two years delayed, I will ask the consultant to explain the letter he/she signed.😂😂🤡🌎 should be an interesting conversation.
Spinelessness and groupthink. Unfortunately, doctors are human like everyone else. I'd love to hear how your consultant responds.
They never read Dr. Jessica' s Substack, and forgot there are Immunology texts available to review mechanisms of action of the immune system.They failed due diligence to protect their patients.
Well there’s some “science” for you. The real deal. Thank you!
My journey with vaccines in general started after my daughter was born. Home birth, NYC. 1988. 5th floor East Village walk up.
My mother-in-law asked me at one point if I was going to vaccinate my daughter. I was like oh! Let me check into that. My two reference books were “How to Raise a Healthy Child in Spite of your Doctor” and one I can’t quite remember the name written by a doctor that was a resource for new moms, including home made formula. Yes, I was a “hippy” Mom. Anyways, they both had chapters dedicated to vaccines. After reading those I went into shock and fear about vaccinating my daughter. The charts that showed the waning of the diseases prior to the introduction of the vaccines. The increase in polio in Sweden After the vaccines were introduced, etc. I chose to not vaccinate my daughter. Joined a group of new Mon’s who were against vaccinating their babies. Lots of resources and support from a small group of doctors were available back then.
The book “DPT, a shot in the dark” came out.
I was lucky to be able to have a vaccine exemption for my daughter and later my son in NY. That’s gone now.
I never took my kids to the doctor unless absolutely necessary. I had a “first aid” kit that had homeopathic medicines and eichanacea. That was all we every needed. Eichanacea tincture drops immediately upon cold symptoms. Zap! Over. Immune system power booster…
I moved to Woodstock NY in 1990. My new neighbor had two girls close to my daughter’s age. She had chosen to not vaccinate her first child. But she was a Mom who took her child in for all those well baby “checkups” that we were told to do. One time, when her daughter was 18 months old, a healthy thriving energetic child, she was bullied and pressured to give her daughter a vaccine. She caved. Immediately afterwards her daughter had a high fever, became sluggish and despondent and never recovered. She was then diagnosed with leukemia. This was when the periwinkle plant had been discovered as an effective chemotherapy treatment for childhood leukemia, which previously was a slow death sentence. $100,000 later, her daughter fully recovered. Was never given another vaccine and next child not vaccinated. A “coincidence”? She and I don’t think so.
I watched the advent of autism unfold. Read Mothering Magazine. The heartbreaking stories and the doctors who were trying to treat. The articles about vaccine dangers.
When my son was born in hospital in 1996 (I had gestational diabetes) I signed paperwork refusing the Hepatitis B vaccine for my newborn. Who the hell thinks that vaccine is needed at birth?? Or at any point for a child?
Fast forward to Covid. My brother was in full remission from HPV throat cancer for over a year. Got the Covid vaccine. 2 months later his cancer returned aggressively and despite all the treatments, they could not stop it. He died this August. Heart attack is what my sister in law thinks. She found him dead at the side of his bed.
These Covid “vaccines” are Killers. They are in the gene therapy classification which under “normal” circumstances would have to go through 8-10 years of trials. Not 2 months. These are a science experiment that has gone south. Actually to hell. We are inheriting the whirlwind here. With so many lives having been needlessly lost and others’ health irreparably damaged. Beyond a living nightmare.
I feel the same about many other childhood vaccines. That are bombarding an undeveloped immune system with substances that we are not even allowed to know what the ingredients are. “Trust us” “They are safe”. I watched Del and Gert lock horns about vaccines. I am not buying the “herd immunity” stance that Gert is taking. Question, haven’t all the “at risk” population that Gert was referring to already been vaccinated?
Realize this is a rambling post. So few people to talk to about this.
Jessica, you are doing incredible work. Thank you from the bottom of my heart! You are a fearless warrior. A true leader of the tribe of Truth. Be well. Keep riding that wave!
Brilliant, reflective, mindful story. Thank you. And so sorry for your friend who got bullied. One sees red....
Thank you, from the heart.
Yes… Thank God she recovered. When I took my son to the doctor because he had a watermelon seed in his ear (!), he and the nurse looked at me like I was a child abuser when I told them my son wasn’t vaccinated. Their hands were practically twitching (literally!) to give him some vaccines. I swear if they could have reported me they would have. On the spot.
Doctors are so poorly educated about vaccines.
I went to Dr. Paul Marik’s trial in Virginia this past fall. To protest and show support. I sat directly behind him in the court room, brought him water. The trial was a nightmare. Lawyer and hospital representative were Horrid.
Afterwards we spoke. He had just read the new Dr. Fauci book. Twice. He stated that he had done a total 180 about vaccines after reading it. Mentioned the word Evil twice.
Big Pharma’s get out of jail free card in 1986 has caused nothing but damage to our children.
As most parents operate from blind obedience to the all mighty doctors. With Big P leading the way.
Thanks be for the light that shines through this covid darkness.... the silver lining maybe, that more and more parents will realize that they've been bought and sold all along...
Thank you for sharing. Can you enlarge upon your disagreement with Dr. Vanden Bossche. The vaccinated are in fact the at risk population, as vaccine induced immunity is much inferior to herd immunity conferred by means of innately-naturally produced immunity according to Dr. Vanden Bossche.
From a colleague: "No discussion on autoimmunity and tolerance is complete without reference to cancer.
Defending against cancer requires controlled autoimmunity and breaking tolerance. Low-affinity self-reactive (LASR) T cells recognize antigens that differ from self by one or more amino acid residues. They are ideally suited to recognize cancer cells and when activated, kill cancer cells.
Animal/plant proteins (xenogeneic antigens), human proteins (allogeneic antigens) that contaminated vaccines/biologics are ideally suited to break tolerance and cause autoimmunity.
In fact, oncologists do exactly that.
Xenogeneic therapeutic cancer vaccines as breakers of immune tolerance for clinical application: to use or not to use?
For lay persons: https://childrenshealthdefense.org/news/vaccines-containing-animal-plant-fungal-proteins-cause-autoimmune-diseases-and-cancer/
For experts: Cancer immunology, bioinformatics and chemokine evidence link vaccines contaminated with animal proteins to autoimmune disease: a detailed look at Crohn's disease and Vitiligo
In healthy people, spike levels upon infection should be low and unlikely to cause problems. In the vaccine-damaged (traditional non-covid vaccines), the immune misfiring upon infection can result in high spike protein levels that could cause autoimmunity as you propose.
Thanks,
Vinu"
Jessica, you are a great writer but this is one of your most lucid pieces ever. Will be passing out to medical students to see if they can think at all...Lots thought provoking in here. Many thanks.
Of course, why would you think to include a 3'UTR that has HUMAN RNA in it (part of the AES tumour suppressor and 12s mitochondrial RNA), downstream of two dysfunctional stop codons (because you used Pseudo-uridine which makes them invisible) and not expect any autoimmune disease? Add in the dysregulation of Th17 and IL-6 and make sure your product makes its way to the spleen and there you go. Oh and don't forget a bit of amyloid. A ticking time bomb of autoimmune disease. Well done Ugur, now you can go and do one of your celebratory rituals. What have you got next in line for us? https://pubmed.ncbi.nlm.nih.gov/30638957/
Nice job. Pomegranate peel/extract could help with promoting Treg cells and downregulating the inflammatory cytokines. Too much is not better and can be inflammatory.
"PoPEx differently modulated the expression of activation markers (CD69, CD25, ICOS) and PD1 (inhibitory marker), depending on the dose and T-cell subsets. PoPEx (starting from 12.5 µg/mL) suppressed the production of Th1 (IFN-γ), Th17 (IL-17A, IL-17F, and IL-22), Th9 (IL-9), and proinflammatory cytokines (TNF-α and IL-6) in culture supernatants. Lower concentrations upregulated Th2 (IL-5 and IL-13) and Treg (IL-10) responses as well as CD4+CD25hiFoxp3+ cell frequency. Higher concentrations of PoPEx increased the frequency of IL-10- and TGF-β-producing T-cells (much higher in the CD4+ subset)." (Colic, et al., 2022)
Immunomodulatory Properties of Pomegranate Peel Extract in a Model of Human Peripheral Blood Mononuclear Cell Culture, https://pubmed.ncbi.nlm.nih.gov/35745713/
Adequate vitamin D levels are essential for Tolerance and requires adequate magnesium to be possible. Avoiding glyphosate may also be a need for good vit D metabolism.
Vitamin C is very helpful for reducing IL6.
Vitamin C reduces interleukin-6 plasma concentration: a systematic review and meta-analysis of randomized clinical trials, https://www.sciencedirect.com/science/article/pii/S2667268521000358
Regarding Glyphosate - also in my email inbox: "CDC finds glyphosate in 80% of US urine samples—as reported by 0% of "our free press"" - Mark Miller, https://markcrispinmiller.substack.com/p/cdc-finds-glyphosate-in-80-of-us?utm_source=%2Finbox&%3Butm_medium=reader2&utm_medium=email
Glyphosate is a big issue and would be a risk factor for more severe CoV or misfolded protein conditions.
Very interesting indeed. Would you consider reaching out to Dr Been to discuss this? An example of his work: https://m.youtube.com/watch?v=AE7LUtAfVZE
science: not so much about finding answers than about finding the questions....
Another exceptional write up. Well done Jessica! If you're right about over-expression of IL-6, I wonder if there could be a similar mechanism of action in any of the current, non-MRNA vaccines. IL-6 has been shown to up-regulate itself in a positive feedback loop (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077634) leading to MS. I've had my suspicions since I developed gluten intolerance (also autoimmune) not long after my only influenza shot. This is of course, difficult to prove, but a cursory look through OWID shows an inbalance in prevalence of most autoimmune diseases and not surprisingly, they are far less common in S. America, Africa, and Asia. Sensibly, we do not find autoimmune diseases in wild/non-domesticated animals so it wouldn't at all surprise me they are, to a large degree, self-inflicted.
Another hypothesis involves biomimicry and pathogenic priming--that is, the SARS-CoV-2 virus was designed with many human-like epitopes that trigger autoimmunity, especially in immune systems that have had prior exposures to similar coronaviruses (more likely in the elderly).
https://www.sciencedirect.com/science/article/pii/S2589909020300186?via%3Dihub
From the author: "In the case of SARS-CoV-2, B-cell mediated autoimmunity was predicted by 27 autoreactogenic epitopes--1/3 were predicted to target immune cells."
The paper, Unbalanced neonatal CD4+ T-cell immunity. August 27, 2017
does not specifically answer the question posed about the injection of Covid19 products, however the authors advise caution in developing vaccines for infants writing:
caution should be taken as induction of strong Th17-type responses could possibly break the induction of immune tolerance to self antigens and favor the development of autoimmunity. The default generation of Tregs in neonates could furthermore promote the Th17 pathway by producing one of its differentiation cytokine, TGFβ (31–33), which could lead to an uncontrolled inflammatory response
https://www.readcube.com/articles/10.3389/fimmu.2014.00393
John Kim, also on Substack, has spoken about findings that the mRNA injectable product can be linked to autoimmune disease:
https://www.rokfin.com/post/77302/Swedish-Scientists-Find-Pfizer-mRNA-Vaccine-Link-to-AutoImmune-Disease-Part-2
Jessica wrote: Is the spike protein destroying tolerance itself?
Good question. It hit me when I read it that perhaps it is culture wide. Something in the air, water or food has caused lots of people to lose tolerance for themselves and each other. Is it the global application of COVID-19 injectable products?
On another subject. In "You can quote me." You mention your age. My wife and I have talked about that before. We couldn't tell how old you are. Look 37 to us.
Be well
Well, we have heard Pfizer CEO saying he hopes for 50% reduction of human population. Will people keep getting jabs knowing this is the plan?
Can we get on this??? Seriously https://palexander.substack.com/p/patterson-et-al-covid-vaxxed-persons/comments#comment-7768718
Neat hypothesis! Thanks for the lecture on auto immunology as well.
A while back you wrote about how you self-treated what was diagnosed as “illness-induced asthma”. Can you tell us more about how you achieved that? Thank you!